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LIVING TO 120 WITH EASE New drug could fight
Alzheimer’s, lung disease, even aging
CONTACT: Genevieve Haas: 617-373-5470
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(7-3-03) BOSTON, Mass. – A
new pill, developed by CereMedix,
a biotech startup at Northeastern University, could restore
the body’s natural defenses so drastically that people might
routinely live to be a healthy 120 years old, researchers
say. | The substance, which
promotes the production of natural anti-oxidants, is set to be
tested in two prescription forms, one designed to repair lung damage
from smoking and the other to speed recovery from heart
surgery.
In prescription form, the drug could have valuable applications for
a wide range of ailments, including Alzheimer’s Disease, stroke and
coronary damage, diabetes and virtually any illness that results from
oxidative stress. In addition to the two prescription drugs in trial,
CereMedix has another version in development: an over-the-counter
supplement that would slow aging and increase energy by stimulating
the production of natural anti-oxidants.
The idea of using anti-oxidants is
not new. Found in fruits and vegetables, the enzymes are known to
help repair the body’s natural defenses against aging. Conventional
wisdom holds that, to absorb sufficient quantities of anti-oxidants,
one would have to eat some 30 pounds of fruits and vegetables per
day. But CereMedix–
headed by CEO Steve Parkinson and president and lead
researcher, Victor Shashoua – has developed a substance that
stimulates the production of enough anti-oxidant enzymes to
virtually stop the clock on aging.
Parkinson, a Scottish
entrepreneur and microbiologist, is wary of claiming that he and
Shashoua have discovered the fountain of youth. But Shashoua points
out that genetically, humans are capable of living between 120 and
160 years. However, few even come close, he says, because the human
body is unable to repair the damage caused by aging.
Initial tests have already shown startling successes. A rat that suffered
a stroke was given the medicine and the effects of the stroke were
almost completely reversed. Geriatric mice that received the drug
were permanently rejuvenated. Preliminary tests even indicate that
in cream form, the drug could have a rejuvenating effect on skin,
which is big news for cosmetics companies.CereMedix is part of Northeastern’s
molecular biotechnology initiative and occupies 3,000 square feet
in Northeastern’s state-of-the-art research facility in the Egan Engineering/Science
Research Center.
Northeastern University, a private research
institution located in Boston, Massachusetts, is a world leader in
practice-oriented education. Building on its flagship cooperative
education program, Northeastern links classroom learning with
workplace experience and integrates professional preparation with
study in the liberal arts and sciences. U.S. News & World
Report, in its annual guide America’s Best Colleges, 2003, ranked
Northeastern University number one in the country among programs
that “require or encourage students to apply what they’re learning
in the classroom out in the real world.” In addition, Northeastern's
career services was ranked #1 by Kaplan Newsweek's Unofficial
Insiders Guide to the 320 Most Interesting Colleges and
Universities, 2003 edition. For more information, please visit
http://www.northeastern.edu.
Northeastern University, a
private research institution located in Boston, Massachusetts, is a
world leader in practice-oriented education. Building on its
flagship cooperative education program, Northeastern links classroom
learning with workplace experience and integrates professional
preparation with study in the liberal arts and sciences. U.S. News
& World Report, in its annual guide America’s Best Colleges,
2003, ranked Northeastern University number one in the country among
programs that “require or encourage students to apply what they’re
learning in the classroom out in the real world.” In addition,
Northeastern's career services was top ranked by Kaplan Newsweek's
“Unofficial Insiders Guide to the 320 Most Interesting Colleges and
Universities in 2002.” For more information, please visit
http://www.northeastern.edu.
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